TWiki> CetadObserva Web>Biblioteca>Obra59 (18 Feb 2010, JoenioCosta? ) (raw view)EditAttach
   
WebObraForm
Título Cannabis Vaporizer Combines Efficient Delivery of THC with effective Suppression of Pyrolytic Compounds
Autor GIERINGER, Dale; LAURENT, Joseph St.; GOODRICH, Scott
Ano 2004
FormatoDaObra Artigo em Periódico
Instituição de Origem Journal of Cannabis Terapeutics
Local de Publicação

Instituição Responsável The UK Cannabis Internet Activist
FormatoDisponivel

Número de Páginas 21
Idioma Inglês
Palavras Chave Marijuana, cannabis,vaporization,smoking,harm reduction
Resumo Cannabis vaporization is a technology designed to deliver inhaled cannabinoids while avoiding the respiratory hazards of smoking by heating cannabis to a temperature where therapeutically active cannabinoid vapors are produced, but below the point of combustion where noxious pyrolytic byproducts are formed. This study was designed to evaluate the efficacy of an herbal vaporizer known as the Volcano®, produced by Storz & Bickel GmbH? &Co. KG, Tuttlingen, Germany (http://www.storz-bickel.com). Three 200 mg samples of standard NIDA cannabis were vaporized at temperatures of 155°-218°C. For comparison, smoke from combusted samples was also tested. The study consisted of two phases: (1) a quantitative analysis of the solid phase of the vapor using HPLC-DAD-MS (High Performance Liquid Chromatograph-Diode Array-Mass Spectrometry) to determine the amount of cannabinoids delivered; (2) a GC/MS (Gas Chromatograph/Mass Spectrometer) analysis of the gas phase to analyze the vapor for a wide range of toxins, focusing on pyrene and other polynuculear aromatic hydrocarbons (PAHs). The HPLC analysis of the vapor found that the Volcano delivered 36%-61% of the THC in the sample, a delivery efficiency that compares favorably to that of marijuana cigarettes. The GC/MS analysis showed that the gas phase of the vapor consisted overwhelmingly of cannabinoids, with trace amounts of three other compounds. In contrast, over 111 compounds were identified in the combusted smoke, including several known PAHs. The results indicate that vaporization can deliver therapeutic doses of cannabinoids with a drastic reduction in pyrolytic smoke compounds. Vaporization therefore appears to be an attractive alternative to smoked marijuana for future medical cannabis studies.
Link http://www.ukcia.org/research/CannabisVaporizer.pdf
Referência para Citação GIERINGER, D. Et Al. Cannabis Vaporizer Combines Efficient Delivery of THC with effective Suppression of Pyrolytic Compounds. Journal of Cannabis Terapeutics, Vol. 4(1), 2004.
Observação

Edit | Attach | Print version | History: r1 | Backlinks | View topic | Raw edit | More topic actions
Topic revision: r1 - 18 Feb 2010 - 19:47:24 - JoenioCosta?
 
This site is powered by the TWiki collaboration platformCopyright &© by the contributing authors. All material on this collaboration platform is the property of the contributing authors.
Ideas, requests, problems regarding TWiki? Send feedback